CMM1 - Congenital Mirror Movement disorder 1

The test detects the mutation (c.643_644dup) in the EFNB3 gene that causes Congenital Mirror Movement Disorder 1 (CMM1).
The inheritance is autosomal recessive, meaning that only animals carrying two copies of the mutated gene will be affected.
Affected dogs can exhibit varying degrees of limb paralysis and a characteristic gait characterized by synchronous movements of both hind limbs (“ bunny-hopping gait”)

Application:
- Assessment of the genotype status in breeding planning
- Differential diagnostics for movement disorders in puppies